Amy Sedaris raised some eyebrows on CNN’s New Year’s Eve broadcast … cracking a tongue in cheek transgender joke live on air that left Andy Cohen and Anderson Cooper speechless.

The comedian appeared as one of the show’s guests and during a viewer Q&A, Cooper asked where the best place to meet a man in 2026 might be. Sedaris quickly fired back that it might be in the women’s bathroom, trailing off mid-thought as the comment landed with a thud.

Cooper and Cohen stayed silent, forcing Sedaris to pivot on the fly. She joked maybe Bergdorf Goodman was a better option, then tossed the question back to the hosts, suggesting a fire station. That finally got a laugh, with Cohen playing along.

Later in the segment, Sedaris accidentally dropped an F-bomb while answering another viewer question about the best excuse to get out of a commitment, prompting her to quickly apologize on air.

Despite the brief stumbles, Sedaris largely kept things light though her unfiltered style clearly kept the hosts on their toes.

While Sedaris isn’t known for political comedy, she’s previously been open about her appreciation for LGBTQ+ audiences. In a 2017 interview, she said gay viewers have some of the best senses of humor, adding their acceptance of her work means everything to her.

A New Year’s celebration turned tragic in the Swiss Alps.

Police say several dozen people are presumed dead and around 100 others were injured after a massive fire ripped through a popular bar in the resort town of Crans-Montana Wednesday morning.

Reports say the blaze broke out around 1:30 AM local time at Le Constellation, a bar packed with New Year’s revelers. Authorities say the fire’s cause is still undetermined.

“A large contingent of police, firefighters, and rescue personnel immediately responded to the scene to assist the numerous victims,” police said in a statement, calling the response a major emergency operation.

Crans-Montana is a well known ski destination in Switzerland’s southern Sierre District, drawing tourists from around the world during the winter season especially during the holidays.

One half of the Island Boys didn’t ring in the New Year on a high note … ’cause TMZ has learned Franky Venegas was arrested again in Florida for alleged drug related offenses and is currently behind bars.

Law enforcement tells us Franky was booked into the Collier County Jail in Naples Wednesday night on one count of drug paraphernalia, posing for a fresh mug shot … face tattoos and all.

We’re told Franky has no bond, as he’s being held on a 24 hour hold because he’s already out on bond from a February arrest for delivering/possessing/selling a firearm with an altered serial number.

We broke the story … Franky was arrested in February on drug and firearm charges. The drug count was dropped, but the firearm charge stuck and that’s the case he’s currently out on bond for.

At the time, police also found a brown “MGM” handbag containing a blue spray painted handgun with no serial numbers, a cut straw, and credit cards in Venegas’ name. Another straw with a white powdery substance was allegedly found in the center console.

Franky rose to fame in 2021 with twin brother Alex after their viral hit, “I’m an Island Boy.”