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We studied America’s entrepreneurs and found too many of them were burned out, anxious and depressed

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It’s no secret that entrepreneurs invest heart and soul into starting, running, developing and growing a business. But building a company can come at a cost to personal well-being and therefore to venture success. Our new research reinforces the concept that well-being is more than just personally fulfilling—it actually drives entrepreneurial growth. 

The potential adverse consequences to entrepreneurs when well-being is disregarded are well-documented. One survey revealed that 87% of founders reported experiencing either anxiety, depression or burnout—or all three. Another found that 30% of entrepreneurs acknowledged depression and 27% anxiety, rates well above the 7% prevalence in the overall U.S. population. Additional research shows that entrepreneurs with compromised well-being were less productive, innovative and persistent, leading to lower economic output. Entrepreneurial well-being is a multifaceted concept defined as the experiencing of satisfaction, positive affect, and psychological functioning.

So what’s contributing to these high levels of compromised well-being? Granted, entrepreneurs work hard, sometimes too hard. Many entrepreneurs work 50 to 60 hours per week, often more during the startup phase, compared to the standard 40-hour week for most employees at corporate jobs. Entrepreneurs may also work without clearly defined work-life boundaries and days off—pulling all-nighters, skipping meals and sleep, or forgoing exercise in exchange for logging long hours. The top performers in entrepreneurship average only about six hours of sleep per night.

But work hours alone don’t fully explain the problem. Entrepreneurs are, on the whole, inherently different from corporate employees. Being your own boss, after all, demands the managing of finances, operations, marketing, and human resources. By its very nature—especially its unpredictability, often in the face of limited resources—it risks breeding entrepreneurs who drive themselves too hard.

At the same time, the very nature of entrepreneurship grants a level of freedom that corporate jobs often don’t. Research shows that entrepreneurs have more opportunity to direct their own work, operate with a high degree of autonomy, and draw deep meaning from what they do. But this flexibility can be a double-edged sword. Without clear boundaries, work can easily spill over into personal life. The fast pace, pressure to succeed, and ever-present risk of failure can make it difficult to step back, leading many founders to equate business success with personal success, and neglect to take time to catch a breath.   

No wonder entrepreneurs are so vulnerable to suffering an emotional toll and strained relationships with family, friends and colleagues. The very factors that fuel their ambition can also create a sense of isolation. In some cases, the more successful entrepreneurs get, the lonelier they feel. Dissatisfaction and frustration may lead to burnout, hampering overall performance, notably decision-making.

What we found

In our current research, we conducted surveys, interviews and focus groups with 308 entrepreneurs from different fields and geographical locations globally. Led by Lehigh University in partnership with the Nasdaq Entrepreneurial Center in Silicon Valley and TU Dortmund University in Germany, our preliminary sample found that higher well-being actually benefits founders not only personally but also professionally. Entrepreneurs who report higher well-being are more engaged in their businesses, thereby fueling their incentive to grow their ventures. 

Further, our study shows that entrepreneurs who set work-life boundaries for themselves experience less burnout. Almost half of those who abided by boundaries (45%) reported low burnout, compared to 6% of those who struggled to do so. Non-boundary-setters were almost three times more likely to experience high burnout (67%) than boundary-setters (23%). Also vital was strong community support: entrepreneurs with access to mentors and emotional backing were 50% more likely to report higher resilience and better stress management. 

These findings highlight the value of striking a balance between gung-ho overkill and long-term practicality—in the process, lending a strategic advantage to the quest for entrepreneurial success.

We also identified some key stressors that undermine entrepreneurial well-being. Founders cited financial stress and income instability as major concerns, with 68% uncertain about meeting payroll or personal expenses, leading to exhaustion. Also at issue was work-life balance, with 74% indicating that the demands of business left them little room for self-care. Does any of this have to be so? Should we still see the stereotypical succeed-at-all-costs entrepreneur as a role model? Should we keep glorifying a hustle culture that might threaten health and wellbeing, and that could prevent ventures from surviving and flourishing? 

No, no, no and no. It’s imperative to aggressively challenge the longstanding assumption that entrepreneurs should be willing to sacrifice well-being to achieve financial success. So what to do?

Redefining entrepreneurial success

To start, elevate entrepreneurial well-being to a much higher priority on our global agenda. We should no longer undervalue and overlook the well-being dilemma. Raise awareness of the special obstacles that entrepreneurs confront. Redefine entrepreneurial success as a balance between financial ambition and preference for autonomy with the pursuit of well-being, ideally without jeopardizing either. Implement tactics to build a more sustainable, more compassionate entrepreneurial culture.  

To a certain extent this is already happening. Our research showed, for example, that venture capital firms are starting to recognize the value of investing hard-coded dollars in companies that prize wellbeing enough to retain wellness coaching services, hold wellness retreats and take other measures to promote overall health. Indeed, VC firms such as Balderton, Felicis and Starting Line now operate founder health and performance programs along with coaching and therapy sessions for founders. Early-stage venture fund 11 Tribes proactively invests in the well-being of entrepreneurs.

On a small scale, entrepreneurs can enact measures to help themselves. They should take the time necessary to recharge and refocus to relieve the pressure they might feel. Founders should adopt well-being as a daily practice. Those who pause for breaks, meditate, do yoga, get enough sleep, build a support network and ask for help perform at a higher level.

But on a macro level, organizations and entrepreneurial communities should commit to systemic reform. Although early-stage ventures often lack the resources for full-scale HR teams, founders can take low-cost, high-impact steps, such as fostering psychological safety, implementing workload management, and tracking well-being metrics. Startups that integrate well-being into leadership practices and company policies can lower stress, boost engagement, and ensure that well-being is not an afterthought, but, rather, top of mind.

Just imagine working in an entrepreneurial environment where well-being is valued—where, for example, peers, mentors and investors routinely take a moment to ask a question all too rarely asked: “How are you today?”

The opinions expressed in Fortune.com commentary pieces are solely the views of their authors and do not necessarily reflect the opinions and beliefs of Fortune.

Fortune Global Forum returns Oct. 26–27, 2025 in Riyadh. CEOs and global leaders will gather for a dynamic, invitation-only event shaping the future of business. Apply for an invitation.



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Databricks CEO Ali Ghodsi says company will be worth $1 trillion by doing these three things

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Ali Ghodsi, the CEO and cofounder of data intelligence company Databricks, is betting his privately held startup can be the latest addition to the trillion-dollar valuation club.

In August, Ghodsi told the Wall Street Journalthat he believed Databricks, which is reportedly in talks toraise funding at a $134 billion valuation, had “a shot to be a trillion-dollar company.” At Fortune’s Brainstorm AI conference in San Francisco on Tuesday, he explained how it would happen, laying out a “trifecta” of growth areas to ignite the company’s next leg of growth.

The first is entering the transactional database market, the traditional territory of large enterprise players like Oracle, which Ghodsi said has remained largely “the same for 40 years.” Earlier this year, Databricks launched a link-based offering called Lakehouse, which aims to combine the capabilities of traditional databases with modern data lake storage, in an attempt to capture some of this market.

The company is also seeing growth driven by the rise of AI-powered coding. “Over 80% of the databases that are being launched on Databricks are not being launched by humans, but by AI agents,” Ghodsi said. As developers use AI tools for “vibe coding”—rapidly building software with natural language commands—those applications automatically need databases, and Ghodsi they’re defaulting to Databricks’ platform.

“That’s just a huge growth factor for us. I think if we just did that, we could maybe get all the way to a trillion,” he said.

The second growth area is Agentbricks, Databricks’ platform for building AI agents that work with proprietary enterprise data.

“It’s a commodity now to have AI that has general knowledge,” Ghodsi said, but “it’s very elusive to get AI that really works and understands that proprietary data that’s inside enterprise.” He pointed to the Royal Bank of Canada, which built AI agents for equity research analysts, as an example. Ghodsi said these agents were able to automatically gather earnings calls and company information to assemble research reports, reducing “many days’ worth of work down to minutes.”

And finally, the third piece to Ghodsi’s puzzle involves building applications on top of this infrastructure, with developers using AI tools to quickly build applications that run on Lakehouse and which are then powered by AI agents. “To get the trifecta is also to have apps on top of this. Now you have apps that are vibe coded with the database, Lakehouse, and with agents,” Ghodsi said. “Those are three new vectors for us.”

Ghodsi did not provide a timeframe for attaining the trillion-dollar goal. Currently, only a handful of companies have achieved the milestone, all of them as publicly traded companies. In the tech industry, only big tech giants like Apple, Microsoft, Nvidia, Alphabet, Amazon, and Meta have managed to cross the trillion-dollar threshold.

To reach this level would require Databricks, which is widely expected to go public sometime in early 2026, to grow its valuation roughly sevenfold from its current reported level. Part of this journey will likely also include the expected IPO, Ghodsi said.

“There are huge advantages and pros and cons. That’s why we’re not super religious about it,” Ghodsi said when asked about a potential IPO. “We will go public at some point. But to us, it’s not a really big deal.”

Could the company IPO next year? Maybe, replied Ghodsi.



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New contract shows Palantir working on tech platform for another federal agency that works with ICE

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Palantir, the artificial intelligence and data analytics company, has quietly started working on a tech platform for a federal immigration agency that has referred dozens of individuals to U.S. Immigration and Customs Enforcement for potential enforcement since September.

The U.S. Citizenship and Immigration Services agency—which handles services including citizenship applications, family immigration, adoptions, and work permits for non-citizens—started the contract with Palantir at the end of October, and is paying the data analytics company to implement “Phase 0” of a “vetting of wedding-based schemes,” or “VOWS” platform, according to the federal contract, which was posted to the U.S. government website and reviewed by Fortune.

The contract is small—less than $100,000—and details of what exactly the new platform entails are thin. The contract itself offers few details, apart from the general description of the platform (“vetting of wedding-based schemes”) and an estimate that the completion of the contract would be Dec. 9.Palantir declined to comment on the contract or nature of the work, and USCIS did not respond to requests for comment for this story.

But the contract is notable, nonetheless, as it marks the beginning of a new relationship between USCIS and Palantir, which has had longstanding contracts with ICE, another agency of the Department of Homeland Security, since at least 2011. The description of the contract suggests that the “VOWS” platform may very well be focused on marriage fraud and related to USCIS’ recent stated effort to drill down on duplicity in applications for marriage and family-based petitions, employment authorizations, and parole-related requests.

USCIS has been outspoken about its recent collaboration with ICE. Over nine days in September, USCIS announced that it worked with ICE and the Federal Bureau of Investigation to conduct what it called “Operation Twin Shield” in the Minneapolis-St. Paul area, where immigration officials investigated potential cases of fraud in immigration benefit applications the agency had received. The agency reported that its officers referred 42 cases to ICE over the period. In a statement published to the USCIS website shortly after the operation, USCIS director Joseph Edlow said his agency was “declaring an all-out war on immigration fraud” and that it would “relentlessly pursue everyone involved in undermining the integrity of our immigration system and laws.” 

“Under President Trump, we will leave no stone unturned,” he said.

Earlier this year, USCIS rolled out updates to its policy requirements for marriage-based green cards, which have included more details of relationship evidence and stricter interview requirements.

While Palantir has always been a controversial company—and one that tends to lean into that reputation no less—the new contract with USCIS is likely to lead to more public scrutiny. Backlash over Palantir’s contracts with ICE have intensified this year amid the Trump Administration’s crackdown on immigration and aggressive tactics used by ICE to detain immigrants that have gone viral on social media. Not to mention, Palantir inked a $30 million contract with ICE earlier this year to pilot a system that will track individuals who have elected to self-deport and help ICE with targeting and enforcement prioritization. There has been pushback from current and former employees of the company alike over contracts the company has with ICE and Israel.

In a recent interview at the New York Times DealBook Summit, Karp was asked on stage about Palantir’s work with ICE and later what Karp thought, from a moral standpoint, about families getting separated by ICE. “Of course I don’t like that, right? No one likes that. No American. This is the fairest, least bigoted, most open-minded culture in the world,” Karp said. But he said he cared about two issues politically: immigration and “re-establishing the deterrent capacity of America without being a colonialist neocon view. On those two issues, this president has performed.”



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CoreWeave CEO: Despite see-sawing stock, IPO was ‘incredibly successful’ amid challenges of tariff timing

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CoreWeave has been rocked by dizzying stock swings—with its stock currently trading 52% below its post-IPO high—and a frequent target of market commentators, but CEO Michael Intrator says the company’s move to the public markets has been “incredibly successful. And he takes the public’s mixed reaction in stride, given the novelty of CoreWeave’s “neocloud” business which competes with established cloud providers like Amazon AWS and Google Cloud.

“When you introduce new models, introduce a new way of doing business, disrupt what has been a static environment, it’s going to take some people some time,” Intrator said Tuesday at Fortune’s Brainstorm AI conference in San Francisco. But, he added, more people are beginning to understand the CoreWeave’s business model.

“We came out into one of the most challenging environments,” Intrator said of CoreWeave’s March IPO, which occurred very close to President Trump’s “Liberation Day” tariffs in April. “In spite of the incredible headwinds, we’re able to launch a successful IPO.”

CoreWeave, which priced its IPO at $40 per share, has experienced frequent severe up-and-down price swings in the eight months since its public market debut. At its closing price of $90.66 on Tuesday, the stock remains well above its IPO price.

As Fortune reported last month, CoreWeave’s rapid rise has been fueled by an aggressive, debt-heavy strategy to stand up data centers at unprecedented speed for AI customers. And for now, the bet is still paying off. In its third-quarter results released in November, the company said its revenue backlog nearly doubled in a single quarter—to $55.6 billion from $30 billion—reflecting long-term commitments from marquee clients including Meta, OpenAI, and French AI startup Poolside. Both earnings and revenue came in ahead of Wall Street expectations.

But the numbers were not all celebratory. CoreWeave disclosed a further increase in the debt it has taken on to finance its expansion, and it revised its full-year revenue outlook downward—suggesting that, even with historic demand in the pipeline.

With media headlines calling CoreWeave a “ticking time bomb,” with critics calling out insider stock sales, circular financing accusations and an overreliance on Nvidia, Intrator was asked whether he felt CoreWeave was misunderstood.

“Look, we built a company that is challenging one of the most stable businesses that exist—that cloud business, these three massive players,” he said, referring to AWS, Microsoft Azure and Google Cloud.  I feel like it’s incumbent on CoreWeave to introduce a new business model on how the cloud is going to be built and run. And that’s what we’re doing.” 

He repeatedly framed CoreWeave not as a GPU reseller or traditional data-center operator but as a company purpose-built from scratch to deliver high-performance, parallelized computing for AI workloads. That focus, he said, means designing proprietary software that orchestrates GPUs, building and colocating its own infrastructure, and moving “up the stack” through acquisitions such as Weights & Biases and OpenPipe.

Intrator also defended the company’s debt strategy, saying CoreWeave is effectively inventing a new financing model for AI infrastructure. He pointed to the company’s ability to repurpose power sources, rapidly deploy capacity, and finance large-scale clusters as proof it is solving problems incumbents never had to face.

“When I look back at history of the company, it took us a year with with a company investor like Fidelity, before they were like, ‘Oh, I get it,’” he said. “So look, we’ve been public for eight months. I couldn’t be prouder of what the company has accomplished.” 



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