Rescue service says 4 killed in strike in central Israel, Iran’s supreme leader killed

In a 12-day war in June, Israeli and American strikes greatly weakened Iran’s air defenses, military leadership and nuclear program. But the killing of Khamenei and several top security officials creates a leadership vacuum, increasing the risk of regional instability.

“You have crossed our red line and must pay the price,” Iran’s parliamentary speaker, Mohammad Bagher Qalibaf, said in a televised address Sunday. “We will deliver such devastating blows that you yourselves will be driven to beg.”

Trump warned that any retaliation would only lead to further escalation.

“THEY BETTER NOT DO THAT,” Trump fired back in a social media post. “IF THEY DO, WE WILL HIT THEM WITH A FORCE THAT HAS NEVER BEEN SEEN BEFORE!”

In a sign of how the attack could stoke regional unrest, hundreds of people stormed the U.S. Consulate in Pakistan’s port city of Karachi on Sunday. Police and paramilitary forces used batons and fired tear gas to disperse the crowd, and several people were killed in the clashes, authorities said.

As U.S. and Israeli strikes have pounded Iran, the Islamic Republic has retaliated with missiles and drone attacks on Israel and nearby Arab Gulf countries hosting U.S. forces.

The air war could rattle global markets, particularly if Iran makes the Strait of Hormuz unsafe for commercial traffic. Around 20% of the world’s traded oil passes through the vital waterway, and oil prices are already set for swings.

In repeated barrages at targets across Israel, one person was killed and more than 120 injured, according to authorities. Many missiles were intercepted, the military said.

Israel’s Defense Minister Israel Katz said Sunday that Israel will have “a non-stop air train” of strikes against military and leadership targets in Iran.

Flights across the Middle East were disrupted, and air defense fire thudded over Dubai. The United Arab Emirates’ commercial capital has long drawn business and expatriates by billing itself as a safe haven in a volatile region.

Shrapnel from Iranian attacks on the Emirates’ capital of Abu Dhabi killed two people, state media said, and debris from aerial interceptions caused fires at the city’s main port and on the facade of the iconic Burj Al Arab hotel.

Attacks also extended into Oman — Iran’s longtime interlocutor with the West that hadn’t been drawn into the fray previously.

Saudi Arabia condemned Iran’s attacks on its capital, Riyadh, and eastern region, saying it had successfully intercepted them. The kingdom noted that it had not allowed its airspace or territory to be used to target Iran.

Jordan said it “dealt with” 49 drones and ballistic missiles. Kuwait, Bahrain and Qatar also said they had intercepted projectiles Sunday morning.

In Iraq, a militant group claimed responsibility for a drone attack targeting American bases in Irbil, according to the Rudaw media outlet. Smoke could be seen from an area where the U.S. has an air base there, but it was not immediately clear whether it had been hit.

As supreme leader, Khamenei had final say on all major policies during his decades in power. He led Iran’s clerical establishment and the Revolutionary Guard, the two main centers of power in the governing theocracy.

Though Trump called on Saturday for the Iranian people to “take over” their government, there was no sign in Tehran or elsewhere of unrest.

Iran quickly formed a council to govern the country until a new supreme leader is chosen.

An Iranian diplomat told the United Nations Security Council that hundreds of civilians were killed and wounded in the strikes.

In southern Iran, at least 115 people were reported killed when a girls’ school was struck, and dozens more were wounded, the local governor told Iranian state TV.

Lt. Col. Nadav Shoshani, an Israeli military spokesperson, said he was not aware of any Israeli or American strikes in the area of the school. U.S. Central Command spokesperson Capt. Tim Hawkins said he was aware of those reports and that officials were looking into them.

Iran’s state news agency IRNA said at least 15 people were killed in the southwest, quoting the governor of the Lamerd region, Ali Alizadeh, as saying a sports hall, two residential areas and a hall near a school were hit.

As reports trickled out about Khamenei’s death, eyewitnesses in Tehran told The Associated Press that some residents were rejoicing, cheering from rooftops, blowing whistles and letting out ululations.

Mourners raised a black flag over the Imam Reza shrine in Mashhad and the Iranian government declared 40 days of public mourning and a seven-day nationwide public holiday to commemorate Khamenei’s death.

Citing unidentified sources, the semiofficial Fars news agency reported that several relatives of Khamenei were also killed, including a daughter, son-in-law, daughter-in-law and grandchild.

Tensions have soared in recent weeks as the Trump administration built up the largest force of American warships and aircraft in the Middle East in decades. The president insisted he wanted a deal to constrain Iran’s nuclear program while the country struggled with growing dissent following nationwide protests.

Democrats decried that Trump had taken action without congressional authorization. The White House said it had briefed several Republican and Democratic leaders in Congress in advance.

Though Trump had pronounced the Iranian nuclear program obliterated in strikes last year, the country was rebuilding infrastructure that it had lost, according to a senior U.S. official who spoke to reporters on condition of anonymity to discuss Trump’s decision-making process. The official said intelligence showed that Iran had developed the capability to produce its own high-quality centrifuges, an important step in developing the highly enriched uranium needed for weapons.

Iran has said it has not enriched since June — though it has maintained its right to do so while saying its nuclear program is entirely peaceful. It has also blocked international inspectors from visiting the sites the U.S. bombed. Satellite photos analyzed by AP have shown new activity at two of those sites, suggesting Iran is trying to assess and potentially recover material.

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Republished with permission of The Associated Press.